Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Brian Tuch
PROVIDER: E-GEOD-20116 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Tuch Brian B BB Laborde Rebecca R RR Xu Xing X Gu Jian J Chung Christina B CB Monighetti Cinna K CK Stanley Sarah J SJ Olsen Kerry D KD Kasperbauer Jan L JL Moore Eric J EJ Broomer Adam J AJ Tan Ruoying R Brzoska Pius M PM Muller Matthew W MW Siddiqui Asim S AS Asmann Yan W YW Sun Yongming Y Kuersten Scott S Barker Melissa A MA De La Vega Francisco M FM Smith David I DI
PloS one 20100219 2
Due to growing throughput and shrinking cost, massively parallel sequencing is rapidly becoming an attractive alternative to microarrays for the genome-wide study of gene expression and copy number alterations in primary tumors. The sequencing of transcripts (RNA-Seq) should offer several advantages over microarray-based methods, including the ability to detect somatic mutations and accurately measure allele-specific expression. To investigate these advantages we have applied a novel, strand-spe ...[more]