Differential expression of Aspergillus genes during the induction of aflatoxin biosynthesis

ABSTRACT: Gene expression analysis of A. parasiticus grown under conditions conducive and nonconductive for aflatoxin production was evaluated using glass slide microarrays containing the 753 ESTs. A complex regulatory network governs the biosynthesis of aflatoxin. While several genes involved in aflatoxin production are known, their action alone cannot account for its regulation. Arrays of clones from an Aspergillus flavus cDNA library and glass slide microarrays of ESTs were screened to identify additional genes. An initial screen of the cDNA clone arrays lead to the identification of 753 unique ESTs. Many showed sequence similarity to known metabolic and regulatory genes; however, no function could be ascribed to over 50% of the ESTs. Gene expression analysis of Aspergillus parasiticus grown un

ORGANISM(S): Aspergillus parasiticus

SUBMITTER: Ahmad Fakhoury 

PROVIDER: E-GEOD-204 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress