Dataset Information
LEOPARD Syndrome iPS, BJ iPS and Fibroblasts
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: R Rozov
PROVIDER: E-GEOD-20473 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome.
Nature 20100601 7299
The generation of reprogrammed induced pluripotent stem cells (iPSCs) from patients with defined genetic disorders holds the promise of increased understanding of the aetiologies of complex diseases and may also facilitate the development of novel therapeutic interventions. We have generated iPSCs from patients with LEOPARD syndrome (an acronym formed from its main features; that is, lentigines, electrocardiographic abnormalities, ocular hypertelorism, pulmonary valve stenosis, abnormal genitali ...[more]
