WT vs KO of lp_2991 comparison
Ontology highlight
ABSTRACT:
ORGANISM(S): Lactobacillus plantarum WCFS1
SUBMITTER: Michiel Wels
PROVIDER: E-GEOD-20515 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Identification of genetic loci in Lactobacillus plantarum that modulate the immune response of dendritic cells using comparative genome hybridization.
Meijerink Marjolein M van Hemert Saskia S Taverne Nico N Wels Michiel M de Vos Paul P Bron Peter A PA Savelkoul Huub F HF van Bilsen Jolanda J Kleerebezem Michiel M Wells Jerry M JM
PloS one 20100513 5
<h4>Background</h4>Probiotics can be used to stimulate or regulate epithelial and immune cells of the intestinal mucosa and generate beneficial mucosal immunomodulatory effects. Beneficial effects of specific strains of probiotics have been established in the treatment and prevention of various intestinal disorders, including allergic diseases and diarrhea. However, the precise molecular mechanisms and the strain-dependent factors involved are poorly understood.<h4>Methodology/principal findings ...[more]
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