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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Expression data of beta-subunit of Snf1 kinase in yeast Saccharomyces cerevisiae

ABSTRACT: The conserved Snf1/AMPK (AMP-activated protein Kinase) family is one of the central components in nutrient sensing and regulation of carbon metabolism in eukaryotes. It is also involved in several other processes such as stress resistance, invasive growth and ageing. Snf1 kinase is composed of a catalytic alpha-subunit Snf1, a regulatory gamma-subunit Snf4 and one of three possible beta-subunits, Sip1, Sip2 or Gal83. We used a systematic approach to study the role of the three beta-subunits by analyzing all 7 possible combinations of beta-subunit deletions together with the reference strain.

ORGANISM(S): Saccharomyces cerevisiae

SUBMITTER: J Zhang

PROVIDER: E-GEOD-20591 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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The beta-subunits of the Snf1 kinase in Saccharomyces cerevisiae, Gal83 and Sip2, but not Sip1, are redundant in glucose derepression and regulation of sterol biosynthesis.

Zhang Jie J Olsson Lisbeth L Nielsen Jens J

Molecular microbiology 20100610 2

The conserved Snf1/AMP-activated protein kinase family is one of the central components in the nutrient sensing and regulation of the carbon metabolism in eukaryotes. It is also involved in several other processes such as stress resistance, invasive growth and ageing. Snf1 kinase is composed of a catalytic alpha-subunit Snf1, a regulatory gamma-subunit Snf4 and one of three possible beta-subunits, Sip1, Sip2 or Gal83. We used a systematic approach to study the role of the three beta-subunits by ...[more]

PMID: 20545859

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