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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Basal Gene Expression Measurements in HEK293T Cells

ABSTRACT: Gene expression microarray profile for human embryonic kidney cells (HEK293T, CRL-11268) under untreated conditions. Gene expression microarray profile for human embryonic kidney cells (HEK293T, CRL-11268) under untreated conditions (DMEM, 10% FBS).

ORGANISM(S): Homo sapiens

SUBMITTER: Russell Thomas

PROVIDER: E-GEOD-21092 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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The identification of protein kinase C iota as a regulator of the Mammalian heat shock response using functional genomic screens.

Boellmann Frank F Thomas Russell S RS

PloS one 20100729 7

<h4>Background</h4>The heat shock response is widely used as a surrogate of the general protein quality control system within the cell. This system plays a significant role in aging and many protein folding diseases as well as the responses to other physical and chemical stressors.<h4>Methods/principal findings</h4>In this study, a broad-based functional genomics approach was taken to identify potential regulators of the mammalian heat shock response. In the primary screen, a total of 13724 full ...[more]

PMID: 20686607

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