Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Jin Hou
PROVIDER: E-GEOD-21279 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Hou Jin J Lin Li L Zhou Weiping W Wang Zhengxin Z Ding Guoshan G Dong Qiongzhu Q Qin Lunxiu L Wu Xiaobing X Zheng Yuanyuan Y Yang Yun Y Tian Wei W Zhang Qian Q Wang Chunmei C Zhang Qinghua Q Zhuang Shi-Mei SM Zheng Limin L Liang Anmin A Tao Wenzhao W Cao Xuetao X
Cancer cell 20110201 2
The full scale of human miRNome in specific cell or tissue, especially in cancers, remains to be determined. An in-depth analysis of miRNomes in human normal liver, hepatitis liver, and hepatocellular carcinoma (HCC) was carried out in this study. We found nine miRNAs accounted for ∼88.2% of the miRNome in human liver. The third most highly expressed miR-199a/b-3p is consistently decreased in HCC, and its decrement significantly correlates with poor survival of HCC patients. Moreover, miR-199a/b ...[more]