Dataset Information
Transcription profiling of mouse epididymal white adipose tissue from C57Bl6 strain after treatment with 3nmol/hr CL 316243 - time series
Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: James Granneman
PROVIDER: E-GEOD-2130 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Metabolic and cellular plasticity in white adipose tissue I: effects of beta3-adrenergic receptor activation.
American journal of physiology. Endocrinology and metabolism 20050607 4
Selective agonists of beta(3)-adrenergic receptors (Adrb3) exhibit potent anti-diabetes properties in rodent models when given chronically, yet the mechanisms involved are poorly understood. A salient feature of chronic Adrb3 activation is pronounced remodeling of white adipose tissue (WAT), which includes mitochondrial biogenesis and elevation of metabolic rate. To gain insights into potential mechanisms underlying WAT remodeling, the time course of remodeling induced by the Adrb3 agonist CL-31 ...[more]
