Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

Expression data of Actinobacillus pleuropneumoniae 4074, the M-NM-^TluxS mutant and AI-2 supplemented M-NM-^TluxS mutant


ABSTRACT: LuxS is an enzyme involved in the activated methyl cycle. The by-product of this cycle, autoinducer 2 (AI-2), could be an important quorum sensing signal. LuxS was conserved and regulated many behaviors in different bacteria, but in most species, whether the regulations are related to AI-2 mediated quorum sensing is still unknown. In our previous study, Actinobacillus pleuropneumoniae, the etiologic agent of porcine contagious pleuropneumonia, was found to possess the functional LuxS affecting biofilm formation and virulence. In this study, microarray was used to compare the transcriptional profiles of the A. pleuropneumoniae wildtype strain 4074, luxS mutant and its AI-2 supplemented strain in four different growth phases. The results demonstrated that both LuxS and AI-2 played important

ORGANISM(S): Actinobacillus pleuropneumoniae

SUBMITTER: Zhuofei Xu 

PROVIDER: E-GEOD-21300 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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