Orchestration of development by the bifunctional transcription factor, APETALA2

ABSTRACT: The emerging picture of transcriptional regulation is one of unexpected complexity. It is now clear that single transcription factors control hundreds, if not thousands, of direct targets by binding their genomic loci, but it is not understood how many of these are major players and how many are supporting cast. To address this, we leverage a well-characterized developmental network in Arabidopsis and map genome-wide binding of related proteins in multiple tissues. The transcription factor APETALA2 (AP2) has numerous functions, including roles in floral organ identity, seed development and stem cell maintenance. We focus on the role of AP2 in the floral transition and map direct targets on a genome-wide scale. We show that ap2 mutants flower early in long and short days, and that AP2 binds

ORGANISM(S): Arabidopsis thaliana

SUBMITTER: Felix Ott 

PROVIDER: E-GEOD-21301 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress