Viral Microarray - Cultured Virus Set

ABSTRACT: Background: The analysis of oligonucleotide microarray data in pathogen surveillance and discovery assays is a challenging task. Target template concentration, nucleic acid integrity, and host nucleic acid composition can each have a profound effect on signal distribution. Exploratory analysis of fluorescent signal distribution in clinical samples has revealed deviations from normality, suggesting that distribution-free approaches should be applied. Results: An examination of both positive predictive value and false positive rates was employed to assess the utility of three well-established nonparametric methods for the analysis of viral array hybridization data: (1) Mann-Whitney U, (2) the Spearman correlation coefficient and (3) the chi-square test. Of the three tests, it was the chi-sq

ORGANISM(S): Influenza A virus (A/Texas/36/1991(H1N1))

SUBMITTER: Omar Jabado 

PROVIDER: E-GEOD-21318 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress