Global gene expression profile of human placental pericytes

ABSTRACT: The objective of this array was to determine the global gene expression profile of human placental pericytes for comparison with other publicly available arrays of pericytes and mesenchymal stromal cells isolated from various human tissues. Pericytes are critical cellular components of the microvasculature that play a major role in vascular development and pathologies, yet their study has been hindered by lack of a standardized method for their isolation and growth. Here we report a method for culturing human pericytes from a readily available tissue source, placenta, and provide a thorough characterization of resultant cell populations. We developed an optimized protocol for obtaining pericytes by outgrowth from microvessel fragments recovered after enzymatic digestion of human placenta

ORGANISM(S): Homo sapiens

SUBMITTER: Cheryl Maier 

PROVIDER: E-GEOD-21332 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress