Effects of ACE2 on BMPR2 mutation-mediated defects in gene expression

ABSTRACT: BMPR2 mutation causes pulmonary arterial hypertension (PAH); ACE2 treatment can resolve established BMPR2-mediated PAH. The purpose of this study was to uncover the molecular mechanism behind this. Four groups: +/- ACE2 and +/- BMPR2 transgene, two arrays each, each array a pool of three animals.

ORGANISM(S): Mus musculus

SUBMITTER: James West 

PROVIDER: E-GEOD-21583 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress