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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Transcription profiling of 22 Pancreatic Cancer Cell Lines

ABSTRACT: We used microarrays to analyze the global expression patterns for 22 commercially available pancreatic cancer cell lines 22 pancreatic cancer cell lines were grown to 80% confluence in DMEM/FBS/PenStrep media and then harvested for total RNA

ORGANISM(S): Homo sapiens

SUBMITTER: Emily Euger

PROVIDER: E-GEOD-21654 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Glycogene expression alterations associated with pancreatic cancer epithelial-mesenchymal transition in complementary model systems.

Maupin Kevin A KA Sinha Arkadeep A Eugster Emily E Miller Jeremy J Ross Julianna J Paulino Vincent V Keshamouni Venkateshwar G VG Tran Nhan N Berens Michael M Webb Craig C Haab Brian B BB

PloS one 20100927 9

<h4>Background</h4>The ability to selectively detect and target cancer cells that have undergone an epithelial-mesenchymal transition (EMT) may lead to improved methods to treat cancers such as pancreatic cancer. The remodeling of cellular glycosylation previously has been associated with cell differentiation and may represent a valuable class of molecular targets for EMT.<h4>Methodology/principal findings</h4>As a first step toward investigating the nature of glycosylation alterations in EMT, w ...[more]

PMID: 20885998

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