Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Mouse Immune system


ABSTRACT: Groups of samples used in Microarray and comparative genomics-based identification of genes and gene regulatory regions of the mouse immune system profiles.

ORGANISM(S): Mus musculus

SUBMITTER: Kathleen Anderson 

PROVIDER: E-GEOD-2168 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Microarray and comparative genomics-based identification of genes and gene regulatory regions of the mouse immune system.

Hutton John J JJ   Jegga Anil G AG   Kong Sue S   Gupta Ashima A   Ebert Catherine C   Williams Sarah S   Katz Jonathan D JD   Aronow Bruce J BJ  

BMC genomics 20041025


<h4>Background</h4>In this study we have built and mined a gene expression database composed of 65 diverse mouse tissues for genes preferentially expressed in immune tissues and cell types. Using expression pattern criteria, we identified 360 genes with preferential expression in thymus, spleen, peripheral blood mononuclear cells, lymph nodes (unstimulated or stimulated), or in vitro activated T-cells.<h4>Results</h4>Gene clusters, formed based on similarity of expression-pattern across either a  ...[more]

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