Expression of JNK target genes during dorsal closure of the Drosophila embryo

ABSTRACT: Morphogenesis of an epithelium relies on the differentiation of cellular territories that further adopt specific cell behavior. During dorsal closure of the Drosophila embryo, distinct territories and several signaling pathways (JNK, Wingless, Dpp, …) bring their own contribution to the migration of the epithelial sheets. In particular, the ectodermal leading edge, which is specified by the JNK pathway, behaves as a purse-string under the action of an acto-myosin cable and as a zipper under the action of cellular extensions. How the leading edge, which is supposed to be a uniform raw of cell, integrates the input of the different signaling pathways is poorly understood. We used microarrays to identify genes whose expression is regulated by the JNK pathway during dorsal closure of the Droso

ORGANISM(S): Drosophila melanogaster

SUBMITTER: Raphael Rousset 

PROVIDER: E-GEOD-21805 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress