Browse
Submit Data
Databases
API
Help

Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

14 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Transcriptome analysis of HepG2 cell with QD655 and QD705 treatments

ABSTRACT: Discovery time-course genome-wide expression profiles in HepG2 cell with QD655 and QD705 treatments to reveal genotoxicity and chronological regulatory pathway Time-course gene expression profiles of HepG2 cell cline with QD655 and QD705 treatments were analyzed. Total RNA were harvested from 4, 8, 12, 24 and 48 hr QD-treated and untreated cells. Human universal reference RNA was used as the reference for all the array experiments. The customized microarrays used were consisted of 49152 probes. Experiments were conducted as two replicates (different cluture).

ORGANISM(S): Homo sapiens

SUBMITTER: Chieh Hua Lin

PROVIDER: E-GEOD-21904 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

ACCESS DATA

Json Xml

Similar Datasets

BV-2 cells treated with different nanoparticles

Project description:BV-2 cells treated with different nanoparticles,including rHDL,PEG-PLA NPs,QD,PEG-QD and AuNP.The cells were treated with NPs for 4h.

2023-10-01 | PXD044395 | Pride

Protein microarray analysis of expression of murine cytokines in spleen interfered with IFN-α and (or) LPS

Project description:12 wild-type C57BL/6 (B6) mice were divided into 4 groups: control group, IFN-α group, LPS group, and IFN-α+ LPS group, every group contained 3 mice (n=3). IFN-α was administrated i.p. to IFN-α group and IFN-α+ LPS group once daily (QD) for 7 days at a medium dose of 105units/kg weight, PBS was administrated i.p. to control group and LPS group QD for 7 days at the same volume. LPS group and IFN-α+ LPS group were injected i.v. with 10 μg LPS for one mouse on the 8th day. Control group and IFN-α group were injected i.v. with PBS at the same volume. 6 h later, mice were sacrificed to harvest spleens for protein microarray experiment. Mouse Cytokine Antibody Array 3(62) was purchased from Ray Biotech, Norcross GA, US. Protein microarray of murine cytokines expression. Spleens from 12 mice (4 group) were treated as indicated in the summary. Equal amount total protein from each spleen was pooled prior to gene expression analysis.

2012-11-10 | E-GEOD-42183 | biostudies-arrayexpress

Human nasopharyngeal carcinoma

Project description:To uncover the oncogenic pathways of nasopharyngeal carcinoma, gene expression profiles of primary NPC cell strains and NPC-derived cell lines were conducted and analyzed in depth. Keywords: Oncogenesis Gene expression profiles of 9 primary NPC cell strains and 5 NPC-derived cell lines were analyzed. Forty Î¼g total RNA from one NPC sample was needed for a dye-swap experiment. Total RNA from 32 normal nasopharyngeal epithelial cell strains was pooled to serve as a universal reference.

2010-05-15 | E-GEOD-14262 | biostudies-arrayexpress

LEC1::GR induction: Establishing the network of seed gene expression and analysis of its biodiversity

Project description:lec1::gr induction - Identification of LEC1 target genes - Induction of 14 days old LEC1::GR seedlings , different treatments (EtOH, DEX, DEX+ABA, induction) for 8 hours 6 dye-swap - CATMA arrays

2011-08-30 | E-GEOD-22173 | biostudies-arrayexpress

12plex_vitis_2011_02_24h

Project description:12plex_vitis_2011-02 - 12plex_vitis_2011_02_24h - Biological question (15 lines max): Identification of grape genes regulated in response to resistance inducer treatments. This transcriptomic analysis should provide insight in the mode of action of the compounds under study and yield generic data relevant to grape defense reaction. 17 dye-swap - normal vs disease comparison,treated vs untreated comparison

2014-09-01 | E-GEOD-54346 | biostudies-arrayexpress

Wild type Lec1 transgene induction by DEX: Establishing the network of seed gene expression and analysis of its biodiversity (wt dex induction)

Project description:wt dex induction - Identification of LEC1 target genes - Induction of 14 days old WT seedlings , different treatments ( EtOH, DEX induction) for 8 hours 2 dye-swap - CATMA arrays

2011-08-30 | E-GEOD-22059 | biostudies-arrayexpress

wt dex induction-Establishing the network of seed gene expression and analysis of its biodiversity

Project description:tri33-lec1 - wt dex induction - Identification of LEC1 target genes - Induction of 14 days old WT seedlings , different treatments ( EtOH, DEX induction) for 8 hours 2 dye-swap - treated vs untreated comparison

2012-03-26 | E-GEOD-36628 | biostudies-arrayexpress

drought and salt stress response-Eskimo gene characterisation.

Project description:ra06-02_staygreen - drought and salt stress response - Modification of the transcriptome by the eskimo mutation and response to stress. - Individual plants were grown in Fertiss clods in a culture chamber. 3 treatments were made to the plants : control, drought and salt. Keywords: gene knock out,treated vs untreated comparison 6 dye-swap - CATMA arrays

2008-09-10 | E-GEOD-10384 | biostudies-arrayexpress

cordycepin-Energetic Homeostasis and Sugar Signaling

Project description:bra-inra09-01_bioen - cordycepin - Diversification of the Molecular Mechanisms Involved in the Control of the Energetic Balance in Angiosperms - To evaluate the importance of mRNA stability control in glucose signaling, genome wide RNA transcript levels changes will be evaluated in response to short term treatments with glucose or glucose plus abscisic acid (ABA) under conditions of transcriptional inhibition in Arabidopsis. The underlying mechanisms will be investigated for a selected number of co-regulated genes (transcription factors, kinases). 12 dye-swap - treatment variations

2012-01-01 | E-GEOD-26045 | biostudies-arrayexpress

Effect of earthworms on Arabidopsis transcriptome

Project description:au07-05_groundworms - groundworms - Do earthworms affect plant growth through signal molecules? - Plants were grown in a sandy soil from the Centre de Recherche en Ecologie Expérimentale et Prédictive (CEREEP, France), in the presence or absence of earthworms. Soil was dried and sieved at 2 mm before to be put in the pots. There was 2 levels of treatment (presence or absence of earthworms in the soil), and 5 plants per treatments. Keywords: treated vs untreated comparison 4 dye-swap - CATMA arrays

2010-09-30 | E-GEOD-24393 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data