Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0

MicroRNAs-449 control vertebrate multi-ciliogenesis by repressing Notch signalling

ABSTRACT: This SuperSeries is composed of the following subset Series: GSE22141: MicroRNA signature during the time course of regeneration of the human airway mucociliary epithelium GSE22142: Transcriptome analysis during the time course of regeneration of the human airway mucociliary epithelium GSE22143: Transcriptomic impact of microRNAs-449 or microRNAs-34 overexpression in proliferating human airway epithelial cells GSE22144: miRNAs high throughput sequencing profiling of regenerating human airway epithelial cells GSE22145: miRNAs high throughput sequencing profiling of basals cells and columnar cells GSE22146: microRNAs signatures of Xenopus laevis embryo epidermis at stage 11 (non ciliated) and 26 (ciliated) using high throughput sequencing Refer to individual Series

ORGANISM(S): Homo sapiens

SUBMITTER: Kevin Lebrigand 

PROVIDER: E-GEOD-22147 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

Json Xml
altmetric image

Publications

Multiciliated cells lining the surface of some vertebrate epithelia are essential for various physiological processes, such as airway cleansing. However, the mechanisms governing motile cilia biosynthesis remain poorly elucidated. We identify miR-449 microRNAs as evolutionarily conserved key regulators of vertebrate multiciliogenesis. In human airway epithelium and Xenopus laevis embryonic epidermis, miR-449 microRNAs strongly accumulated in multiciliated cells. In both models, we show that miR-  ...[more]

Similar Datasets

Transcriptomics miRNAs high throughput sequencing profiling of basals cells and columnar cells
2011-06-06 | E-GEOD-22145 | biostudies-arrayexpress
Transcriptomics miRNAs high throughput sequencing profiling of regenerating human airway epithelial cells
2011-06-06 | E-GEOD-22144 | biostudies-arrayexpress
Transcriptomics MicroRNA signature during the time course of regeneration of the human airway mucociliary epithelium
2011-06-06 | E-GEOD-22141 | biostudies-arrayexpress
Transcriptomics Transcriptome analysis during the time course of regeneration of the human airway mucociliary epithelium
2011-06-06 | E-GEOD-22142 | biostudies-arrayexpress
Transcriptomics microRNAs signatures of Xenopus laevis embryo epidermis at stage 11 (non ciliated) and 26 (ciliated) using high throughput sequencing
2011-06-06 | E-GEOD-22146 | biostudies-arrayexpress
Transcriptomics Transcriptomic impact of microRNAs-449 or microRNAs-34 overexpression in proliferating human airway epithelial cells
2011-06-06 | E-GEOD-22143 | biostudies-arrayexpress
Proteomics In-depth proteomic analysis of nasal fluids from patients with chronic rhinosinusitis and nasal polyps by data-independent acqusition
2021-09-09 | PXD018960 | Pride
Transcriptomics Smoking is Associated with Shortened Airway Cilia
2012-12-13 | E-GEOD-16696 | biostudies-arrayexpress
Unknown Transcriptome analysis during the time course of regeneration of the human airway mucociliary epithelium
2011-06-07 | GSE22142 | GEO
Unknown miRNAs high throughput sequencing profiling of regenerating human airway epithelial cells
2011-06-07 | GSE22144 | GEO