Physiology of Pseudomonas aeruginosa in Biofilms Revealed by Comparative Transcriptomic Analysis.

ABSTRACT: Abstract: Transcriptome analysis was applied to characterize the physiological activities of Pseudomonas aeruginosa grown for three days in drip-flow biofilm reactors. Conventional applications of transcriptional profiling often compare two paired data sets that differ in a single experimentally controlled variable. In contrast this study obtained the transcriptome of a single biofilm state, ranked transcript signals to make the priorities of the population manifest, and compared rankings for a priori identified physiological marker genes between the biofilm and published data sets. Two drip flow biofilm conditions with three replicates each: (1) baseline control at 72hrs, (2) no treatment for 12 hours past baseline. Data from these two conditions were pooled

ORGANISM(S): Pseudomonas aeruginosa

SUBMITTER: Kate McInnerney 

PROVIDER: E-GEOD-22164 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress