Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Transcription profiling of human Caco-2 cells cocultured with E.coli Nissle 1917

ABSTRACT: Confluent Caco-2 cells cultured over 6 hours non-treated with E.coli Nissle 1917; (GSM40938 and GSM40941). Confluent Caco-2 cells cocultured over 6 hours with E.coli Nissle 1917 (GSM40881 and GSM40937).

ORGANISM(S): Homo sapiens

SUBMITTER: Robert Geffers 

PROVIDER: E-GEOD-2232 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

The host response to the probiotic Escherichia coli strain Nissle 1917: specific up-regulation of the proinflammatory chemokine MCP-1.

Ukena Sya N SN   Westendorf Astrid M AM   Hansen Wiebke W   Rohde Manfred M   Geffers Robert R   Coldewey Sina S   Suerbaum Sebastian S   Buer Jan J   Gunzer Florian F  

BMC medical genetics 20051213

<h4>Background</h4>The use of live microorganisms to influence positively the course of intestinal disorders such as infectious diarrhea or chronic inflammatory conditions has recently gained increasing interest as a therapeutic alternative. In vitro and in vivo investigations have demonstrated that probiotic-host eukaryotic cell interactions evoke a large number of responses potentially responsible for the effects of probiotics. The aim of this study was to improve our understanding of the E. c  ...[more]

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