Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Role of Rok in biofilm structure development of Bacillus subtilis 168


ABSTRACT: Comparison of the B subtilis rok mutant vs wild type (sample 1-4) and rok-comK mutant vs comK mutant (sample 5-8) One condition design comparision of (rok vs wt) and (rok-comK vs comK) including a dye swap, 4 biological replicate

ORGANISM(S): Bacillus subtilis

SUBMITTER: Akos Kovacs 

PROVIDER: E-GEOD-22370 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Rok regulates yuaB expression during architecturally complex colony development of Bacillus subtilis 168.

Kovács Akos T AT   Kuipers Oscar P OP  

Journal of bacteriology 20101119 4


Transcriptome analysis of a Bacillus subtilis rok strain that showed reduced complex colony structure formation revealed significant downregulation of the yuaB gene. Overexpression of yuaB restored structure formation in the rok strain. We show that transcription of yuaB is indirectly regulated by Rok, independently from its previously described AbrB-dependent regulation. ...[more]

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