Mouse Models of Alveolar/Embryonal Rhabdomyosarcoma & Spindle Cell Sarcomas

ABSTRACT: A series of conditional mouse models of embryonal rhabdomyosarcoma, alveolar rhabdomyosarcoma and spindle cell sarcoma were generated and validated for relavence to corresponding human cancers. Conditional mouse models of embryonal rhabdomyosarcoma, alveolar rhabdomyosarcoma and spindle cell sarcoma were created by activation or deletion of Pax3:Fkhr, p53, Ptch1 or Rb1 genes.

ORGANISM(S): Mus musculus

SUBMITTER: Hung-I Chen 

PROVIDER: E-GEOD-22520 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress