Protein production by Aspergillus oryzae

ABSTRACT: The filamentous fungus Aspergillus oryzae is an important microbial cell factory for industrial production of useful enzymes, such as α-amylase. In order to optimize the industrial enzyme production process, there is a need to understand fundamental processes underlying protein production, here under how protein production links to metabolism through global regulatory structures. In this study, two α-amylase-producing strains of A. oryzae, a wild type strain and a transformant strain containing additional copies of the α-amylase gene, were characterized at a systematic level. Based on integrated analysis of ome-data together with genome-scale metabolic network and flux calculation, we identified key genes, key enzymes, key proteins, and key metabolites involved in the processes of prot

ORGANISM(S): Aspergillus oryzae

SUBMITTER: wanwipa vongsangnak 

PROVIDER: E-GEOD-22566 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress