Expression data from human PBMC induced by mixed Congeners of PCBs at Human equivalence

ABSTRACT: Exposure to Polychlorobiphenyls (PCBs) is known to cause serious health effects in human but the gene expression profiles leading to development of different diseases and disorders are not fully understood. The knowledge of global gene expression will help us to develop early disease or disorder biomarkers for PCB induced health effects. We used microarrays to detail the global gene expression profile underlying the effects of mixed PCB exposure at Slovak Human equivalance Level on human PBMC leading to identification of distinct classes of up-regulated and down-regulated genes and cellular processes. PBMC cells are grown for 48 hours in RPMI 1640 supplemented with 10% FBS and 1X Pennicilllin-Streptromycin with 1.25 microgram/ml PHA-M and 0.15% (v/v)pokeweed mitogen and 50 microgram beta-m

ORGANISM(S): Homo sapiens

SUBMITTER: Sisir Dutta 

PROVIDER: E-GEOD-22668 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress