Identification of changes in gene expression in seedlings of the ashh2/sdg8 Arabidopsis mutant

ABSTRACT: Mutation of the ASHH2 gene has pleiotropic developmental effects. The aim of the study was to identify changes in gene expression in seedlings of the ashh2-1/sdg8-1 mutant (SALK_065480, insertion in the gene At1g77300, SDG8/EFS/ASHH2) and look for correlation wth changes in methylation marks on histone tails. Wild type Arabidopsis thaliana (ecotype Colombia) seedlings were used as reference. For low-expresssed tissue-specific genes there was a correlation between reduced H3K36me3 levels and reduction in expression. Although some highly expressed genes with low tissue-specificity show reduced H3K36me3 levels in the mutant, expression levels were, however, not affeccted. Six biological replicates with 12 plants each both of Arabidopsis thaliana wild type (ecotype Colombia-0) and ashh2-1/sg

ORGANISM(S): Arabidopsis thaliana

SUBMITTER: Reidunn Aalen 

PROVIDER: E-GEOD-22990 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress