Genome wide transcriptional profiling of c-Cbl deficient hematopoietic stem and progenitor cells

ABSTRACT: Expression of genes that are differentially expressed between c-Cbl control and c-Cbl mutant hematopoietic stem and progenitor cells were identified through this approach. Interestingly, several leukemia associated genes, particularly transcription factors, were differentially expressed between c-Cbl WT and c-Cbl mutant hematopoietic stem and progenitor cells. Hematopoietic stem and progenitor cells of c-Cbl control and c-Cbl mutant mice were sorted based on their defined immunophenotype. Gene expression studies were performed using Illumina microarray chips.

ORGANISM(S): Mus musculus

SUBMITTER: Chozha Vendan Rathinam 

PROVIDER: E-GEOD-23564 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress