Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Genome-wide expression analysis of dikaryotic colonies of Schizophyllum commune: wild-type, delta-hom2, delta-fst4

ABSTRACT: The transcription factors Hom2 and Fst4 were shown to be involved in mushroom development in the basidiomycete Schizophyllum commune. When the genes encoding Hom2 or Fst4 were deleted, no mushrooms formed. In this study we performed a genome-wide expression analysis on dikaryons of wild-type, delta-hom2 and delta-fst4. A total of three samples were analyzed. One wild-type and two deletion strains (delta-hom2 and delta-fst4)

ORGANISM(S): Schizophyllum commune

SUBMITTER: H.A.B. Wösten 

PROVIDER: E-GEOD-23594 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Transcription factor genes of Schizophyllum commune involved in regulation of mushroom formation.

Ohm Robin A RA   de Jong Jan F JF   de Bekker Charissa C   Wösten Han A B HA   Lugones Luis G LG  

Molecular microbiology 20110804 6

Mushrooms represent the most conspicuous structures of fungi. Their development is being studied in the model basidiomycete Schizophyllum commune. The genome of S. commune contains 472 genes encoding predicted transcription factors. Of these, fst3 and fst4 were shown to inhibit and induce mushroom development respectively. Here, we inactivated five additional transcription factor genes. This resulted in absence of mushroom development (in the case of deletion of bri1 and hom2), in arrested devel  ...[more]

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