Pervasive gene content variation and copy number variation in both maize and its undomesticated progenitor

ABSTRACT: Different individuals of the same species are generally thought to have very similar genomes. However, there is growing evidence that structural variation in the form of copy number variation (CNV) and presence-absence variation (PAV) can lead to variation in the genome content of individuals within a species. In order to investigate the potential contribution of CNV and PAV to genomic diversity in maize we used array comparative genomic hybridization (CGH) to compare gene content and copy number variation among 25 diverse maize inbreds 14 genotypes of the wild ancestor of maize, teosinte. The microarray included multiple probes for each of the ~32,500 stringently filtered genes identified in the B73 reference genome. We identified 479 genes exhibiting higher copy number in some genotypes

ORGANISM(S): Zea mays

SUBMITTER: Peter Tiffin 

PROVIDER: E-GEOD-23756 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress