Transcription profiling of mouse CD4 cells isolated from an ENU induced mutant Sanroque vs. wildtype

ABSTRACT: Male C57BL/6 mice were treated with ENU to generate single base substitutions, the variant genome sequences were breed to homozygosity in inbreeding pedigrees, and screened for antinuclear autoantibodies (ANA). The sanroque pedigree contained multiple progeny with ANA of mixed homogeneous nuclear and cytoplasmic immunofluorescence pattern by 12 weeks of age, due to an autosomal recessive gene variant. Comparison of the gene expression profile of CD4 cells from Sanroque to wild type was performed.

ORGANISM(S): Mus musculus

SUBMITTER: Teresa Lambe 

PROVIDER: E-GEOD-2376 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress