Transcription profiling of glioblastoma primary culture treated with TGF-beta receptor inhibition.

ABSTRACT: TGF-beta has an oncogenic response in glioblastoma and it is considered to be a therapeutic target. We evaluated the effect of TGF-beta inhibition in glioblastoma. Differential gene expression analysis of patient-derived primary cultured glioblastoma cells treated with the TGF-beta receptor inhibitor, LY2109761 11 patient-derived cell cultures from 11 patients were treated with 2microM of the TGF-beta receptor inhibitor, LY2109761, for 3 hours or left untreated and RNA was isolated and microarray analysis was performed

ORGANISM(S): Homo sapiens

SUBMITTER: Joan Seoane 

PROVIDER: E-GEOD-23935 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress