Transcriptome analysis of glucose starved Bacillus subtilis cells

ABSTRACT: In this study, temporal changes in the proteome, transcriptome and extracellular metabolome of B. subtilis caused by glucose starvation were monitored. For proteomic profiling, a combination of in vivo metabolic labeling and shot gun mass spectrometric analysis was carried out for five different proteomic subfractions (i. cytosolic, ii. extracellular, iii. membrane, iv. integral membrane, and v. surface proteome fraction) leading to the identification of about 52% of the predicted proteome of B. subtilis. Acquired proteomic and transcriptomic data were analyzed using Voronoi treemaps which link functional classifications and relative expression changes of gene products according to their fate in the stationary phase. The data obtained enables for in-depth analysis of major physiological pr

ORGANISM(S): Bacillus subtilis subsp. subtilis str. 168

SUBMITTER: Ulrike Mäder 

PROVIDER: E-GEOD-24058 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress