Transcription profiling of human mesenchymal stem cell derived stromal and adipocyte cells treated with insulin.

ABSTRACT: There are an estimated 21million diabetics in the United States and 150 million diabetics worldwide. The World Health Organization anticipates that these numbers will double in the next 20 years. Metabolic syndrome is a well recognized set of symptoms that increases a patient’s risk of developing diabetes. Insulin resistance is a factor in both metabolic syndrome and Type 2 diabetes. It is characterized by decreased insulin stimulated glucose uptake in peripheral tissues, decreased adiponectin levels, increased adipocyte FFA and cytokine production, and increased insulin and hepatic glucose output. Prevention or reversal of insulin resistance should serve as an important strategy in addressing the growing health concerns posed by the Diabetes epidemic. While increased adiposity is asso

ORGANISM(S): Homo sapiens

SUBMITTER: Shelley des Etages 

PROVIDER: E-GEOD-24422 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress