Evolution of S. cerevisiae - S. bayanus Interspecific Hybrids

ABSTRACT: Hybrid progeny can enjoy increased fitness and stress tolerance relative to their ancestral species, a phenomenon known as hybrid vigor. Though this phenomenon has been documented throughout the Eukarya, evolution of hybrid populations has yet to be explored experimentally in the lab. To fill this knowledge gap we created a pool of Saccharomyces cerevisiae and S. bayanus homoploid and aneuploid hybrids, and then investigated how selection in the form of incrementally increased temperature or ethanol impacted hybrid genome structure and adaptation. During 500 generations of continuous ammonia-limited, glucose-sufficient culture, temperature was raised from 25C to 46??C. This selection invariably resulted in nearly-complete loss of the S. bayanus genome, although the dynamics of genome loss

ORGANISM(S): Saccharomyces bayanus x Saccharomyces cerevisiae

SUBMITTER: Barbara Dunn 

PROVIDER: E-GEOD-24479 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress