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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Heat shock: genomic run-on (GRO) analysis

ABSTRACT: This SuperSeries is composed of the following subset Series: GSE24483: TR heat-shock GSE24484: RA heat-shock Refer to individual Series

ORGANISM(S): Saccharomyces cerevisiae

SUBMITTER: Jose Perez-Ortin

PROVIDER: E-GEOD-24488 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Heat shock response in yeast involves changes in both transcription rates and mRNA stabilities.

Castells-Roca Laia L García-Martínez José J Moreno Joaquín J Herrero Enrique E Bellí Gemma G Pérez-Ortín José E JE

PloS one 20110225 2

We have analyzed the heat stress response in the yeast Saccharomyces cerevisiae by determining mRNA levels and transcription rates for the whole transcriptome after a shift from 25 °C to 37 °C. Using an established mathematical algorithm, theoretical mRNA decay rates have also been calculated from the experimental data. We have verified the mathematical predictions for selected genes by determining their mRNA decay rates at different times during heat stress response using the regulatable tetO p ...[more]

PMID: 21364882

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TR heat-shock

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2011-04-19 | E-GEOD-24483 | biostudies-arrayexpress

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