Gene Expression profile in preimplantation in vitro embryos derived from Prepubertal heifers and Adult Cattle

ABSTRACT: Age of the donor animal has a significant influence on the oocyteM-bM-^@M-^Ys ability to complete maturation and acquire the mRNA and proteins required for normal embryonic development. It is well known that developmental competence is reduced in oocytes derived from juvenile animals when compared to that derived from adults. However, the molecular mechanisms associated with these differences are not well elucidated. The aim of this study was to analyze the transcriptome differences between adult versus prepubertal derived preimplantation embryos and to identify genes associated with oocyte developmental potential. We performed cDNA microarray analysis on populations of preimplantation embryos (8- to 16-cell and Day 7 blastocysts) derived from adult versus prepubertal Japanese Black cattle

ORGANISM(S): Bos taurus

SUBMITTER: Dorji Dorji 

PROVIDER: E-GEOD-24596 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress