Gene expression profile of probiotic Lactobacillus casei Zhang during the late stage of milk fermentation

ABSTRACT: Lactobacillus casei Zhang is a probiotic bacterium isolated from koumiss in Inner Mongolia of China that has been commercially used as a starter in the manufacture of dairy products. To study the gene expression profiles of L. casei Zhang during growth in milk, a whole-genome microarray was used. Compared to L. casei Zhang grown to late logarithmic phase in milk, 61 genes were significantly up-regulated (>5 fold) in stationary phase, whereas 26 genes were down-regulated. Collectively, these data showed that the majority of the identified genes was involved in carbohydrate metabolism and energy production, followed by genes involved in nucleotide metabolism, inorganic ion transport, amino acid transport and metabolism, chaperone, etc. This study demonstrates the fundamental effects of cultu

ORGANISM(S): Lactobacillus casei str. Zhang

SUBMITTER: Heping Zhang 

PROVIDER: E-GEOD-24597 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress