A phylogenetically based transcriptome age index mirrors ontogenetic divergence patterns

ABSTRACT: Parallels between phylogeny and ontogeny have been discussed since almost two centuries and a number of theories have been proposed to explain such patterns. Especially elusive is the so-called phylotypic stage, a phase during development where species within a phylum are particularly similar to each other. While this has formerly been interpreted as a recapitulation of phylogeny, it is nowadays thought to reflect an ontogenetic progression phase, where strong constraints on developmental regulation and gene interactions exist. Several studies have shown that genes expressed during this stage evolve slower, but it has so far not been possible to derive an unequivocal molecular signature associated with this stage. We use here a combination of phylostratigraphy and stage specific gene expre

ORGANISM(S): Danio rerio

SUBMITTER: Tomislav Domazet-Loso 

PROVIDER: E-GEOD-24616 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress