Dataset Information
Transcription profiling by array of testis from four Mus musculus species to study the differential gene expression
Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus castaneus
SUBMITTER: Chris Voolstra
PROVIDER: E-GEOD-2471 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
A change of expression in the conserved signaling gene MKK7 is associated with a selective sweep in the western house mouse Mus musculus domesticus.
Journal of evolutionary biology 20060901 5
Changes in gene expression are known to occur between closely related species, but it is not yet clear how many of these are due to random fixation of allelic variants or due to adaptive events. In a microarray survey between subspecies of the Mus musculus complex, we identified the mitogen-activated protein-kinase-kinase MKK7 as a candidate for change in gene expression. Quantitative PCR experiments with multiple individuals from each subspecies confirmed a specific and significant up-regulatio ...[more]
