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Transcription profiling of human glioblastoma pseudopalisading cells

ABSTRACT: By comparing to common tumor cells, genes were differencially expressed in pseudopalisading cells in human glioblastoma

ORGANISM(S): Homo sapiens

SUBMITTER: Shumin Dong

PROVIDER: E-GEOD-2485 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Histology-based expression profiling yields novel prognostic markers in human glioblastoma.

Dong Shumin S Nutt Catherine L CL Betensky Rebecca A RA Stemmer-Rachamimov Anat O AO Denko Nicholas C NC Ligon Keith L KL Rowitch David H DH Louis David N DN

Journal of neuropathology and experimental neurology 20051101 11

Although the prognosis for patients with glioblastoma is poor, survival is variable, with some patients surviving longer than others. For this reason, there has been longstanding interest in the identification of prognostic markers for glioblastoma. We hypothesized that specific histologic features known to correlate with malignancy most likely express molecules that are directly related to the aggressive behavior of these tumors. We further hypothesized that such molecules could be used as biom ...[more]

PMID: 16254489

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