MYC drives resistance to PI3K/mTOR targeted inhibition (gene expression)

ABSTRACT: Gene expression signatures were measured after treatment of cells with 50nM BEZ235. Affymetrix HG-U133AV2 expression arrays were performed according to the manufacturer's directions using RNA extracted by Qiagen RNeasy from engineered human cell-lines grown for 72h in the presence of 50nM BEZ235 Resulting expression signatures where derived based on phenotypic properties(resistance to BEZ235) of the cells (enriched vs GFP/HR).

ORGANISM(S): Homo sapiens

SUBMITTER: Nina Ilic 

PROVIDER: E-GEOD-25172 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress