Gene expression profiling of mesial temporal lobe epilepsy

ABSTRACT: The epilepsies represent one of the most common neurological disorders. Mesial temporal lobe epilepsies (MTLE) are the most frequent form of partial epilepsies and display frequent resistance to anti-epileptic drugs thus representing a major health care problem. In TLE, the origin of seizure activity typically involves the hippocampal formation, which displays major neuropathological features, described with the term hippocampal sclerosis (HS). HS is the most frequent pathological substrate of refractory mesial temporal lobe epilepsy. Complex partial seizures (CPS) are the predominant seizure type associated with medial temporal lobe epilepsy. MTLE is commonly due to mesial temporal sclerosis (MTS). The biology underlying the epilepstic seizures and the transcriptome associated to the seiz

ORGANISM(S): Homo sapiens

SUBMITTER: Akhilesh Pandey 

PROVIDER: E-GEOD-25453 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress