Transcriptome analysis of avian pathogenic Escherichia coli O1 in chicken serum compared to LB

ABSTRACT: Colisepticemia caused by avian pathogenic Escherichia coli (APEC) results in annual multimillion dollar losses to the poultry industry. Recent research suggests that APEC may have an important role in public health as well. Generally, colisepticemia follows a respiratory tract infection in which APEC penetrate the respiratory epithelium to enter the bloodstream. From the bloodstream, bacteria may spread to various internal organs resulting in perihepatitis, pericarditis, and other conditions. The aim of this study was to identify molecular mechanisms enabling APEC to survive and grow in the bloodstream. To do so, we compared the transcriptome of APEC O1 during growth in Luria-Bertani broth and chicken serum. Selected genes that were significantly up-regulated in chicken serum were then su

ORGANISM(S): Escherichia coli APEC O1

SUBMITTER: Chrystala Constantinidou 

PROVIDER: E-GEOD-25478 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress