CAMP/PKA signaling balances respiratory activity with mitochondria dependent apoptosis via transcriptional regulation

ABSTRACT: This data provides evidence that elevation of cAMP levels has a dramatic effect on the transcriptome of yeast cells, with particular emphasis on mitochondrial function and the promotion of ROS production S. cerevisiae cells lacking the high affinity phosphodiesterase PDE2or both PDE2 and the PKA subunit TPK3 were grown for 24h in rich media in the presence of 4mM exogensously added cAMP. 8 samples.

ORGANISM(S): Saccharomyces cerevisiae

SUBMITTER: Campbell Gourlay 

PROVIDER: E-GEOD-25541 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress