Microarray analysis highlights immune response of Pacific oysters as a determinant of resistance to summer mortality

ABSTRACT: Summer mortality of Crassostrea gigas is the result of a complex interaction between oysters, their environment and pathogens. A large genetic basis and a high heritability were demonstrated for the observed variation in resistance to summer mortality, which offered the possibility to develop lines of oysters that were resistant (R) or susceptible (S) to summer mortality. Previously, genome-wide expression profiling of R and S oyster gonads highlighted reproduction and antioxidant defense as constitutive pathways that operate differentially between these two lines. Here, we show that signaling in innate immunity also operates differentially between these lines and we postulated that it is at the main origin of their difference of survival in the field. From the already published microarray

ORGANISM(S): Crassostrea gigas

SUBMITTER: Arnaud Huvet 

PROVIDER: E-GEOD-25614 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress