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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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SAGE analysis of Type 2 Gaucher brain

ABSTRACT: This library was constructed from mRNA derived from an eight month old female with type 2 Gaucher disease according to the SAGE protocol of V. E. Velculescu et al. (1995), in the laboratory of R. L. Proia (NIDDK, NIH). This GEO Series was created by the GEO staff as part of a cleanup effort to ensure that all GEO Samples are included within a Series entry.

ORGANISM(S): Homo sapiens

SUBMITTER: Richard Proia

PROVIDER: E-GEOD-25756 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Global gene expression in a type 2 Gaucher disease brain.

Myerowitz Rachel R Mizukami Hiroki H Richardson Kristine L KL Finn Laura S LS Tifft Cynthia J CJ Proia Richard L RL

Molecular genetics and metabolism 20041201 4

Gaucher disease is a member of a family of inherited disorders called sphingolipidoses that among others includes Tay-Sachs and Sandhoff diseases. It is caused by the accumulation of glucosylceramide (glucocerebroside) due to deficient activity of the enzyme glucosylceramide-beta-glucosidase (glucocerebrosidase). As with other glycosphingolipidoses, severe neurodegeneration is present in types 2 and 3 Gaucher disease. We have used Serial Analysis of Gene Expression (SAGE) to characterize the gen ...[more]

PMID: 15589115

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SAGE analysis of Type 2 Gaucher brain

Project description:This library was constructed from mRNA derived from an eight month old female with type 2 Gaucher disease according to the SAGE protocol of V. E. Velculescu et al. (1995), in the laboratory of R. L. Proia (NIDDK, NIH).

2010-12-01 | GSE25756 | GEO

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RL-SAGE analysis of Zea mays leaf transcriptome

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Human_SAGE_cervix_normal_B_1

Project description:Uterine cervix normal SAGE, CGAP non-normalized SAGE library, bulk method , HPV negative This GEO Series was created by the GEO staff as part of a cleanup effort to ensure that all GEO Samples are included within a Series entry.

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