Interlaboratory study to determine the reproducibility of toxicogenomics datasets

ABSTRACT: The application of toxicogenomics as a predictive tool for chemical risk assessment has been under evaluation by the toxicology community for more than a decade. However, toxicogenomics predominately remains a tool for investigative research rather than for regulatory risk assessment. In this study, we aimed to determine whether the current generation of microarray technology in combination with an in vitro experimental design was capable of generating robust, reproducible data of sufficient quality to show promise as a tool for regulatory risk assessment. To this end, we designed a prospective collaborative study to determine the level of inter- and intra-laboratory reproducibility between three independent laboratories. All test sites adopted the same protocols for all aspects of the to

ORGANISM(S): Homo sapiens

SUBMITTER: Yeyejide Adeleye 

PROVIDER: E-GEOD-25936 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress