Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Lin Ju-Sheng
PROVIDER: E-GEOD-26034 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Liu Lifeng L Li Jin J Yao Jinjian J Yu Jinling J Zhang Jinliang J Ning Qin Q Wen Zirong Z Yang Daguo D He Yongwen Y Kong Xinjuan X Song Qilong Q Chen Man M Yang Hong H Liu Qing Q Li Senlin S Lin Jusheng J
Viral immunology 20111001 5
Host genetics play a vital role in determining clinical outcomes of hepatitis B virus (HBV) infection. To identify novel susceptibility loci to HBV progression, we carried out a genome-wide association study with DNA pooling. This study assessed the relationship between 8 highly-ranked SNPs selected from our DNA pool and disease progression of HBV infection in two independent case-control studies. The first population included 628 asymptomatic HBV carriers (AsC) and 1729 progressed HBV carriers ...[more]