Host intelligence in response to bacteriophage c2 infection in Lactococcus lactis IL1403

ABSTRACT: Bacteriophage infection of Lactococcus lactis strains used in the manufacture of fermented milk products is a major threat for the dairy industry. A greater understanding of the global molecular response of the bacterial host following phage infection has the potential to identify new targets for the design of phage control measures for biotechnological processes. In this study, we have used whole-genome oligonucleotide microarrays to gain insights into the genomic intelligence driving the instinctive response of L. lactis subsp. lactis IL1403 to the onset of a challenge with the lytic prolate-headed phage c2. Following phage adsorption, the bacterium differentially regulated the expression of 61 genes belonging to 14 functional categories, and mostly to cell envelope (12 genes), regulator

ORGANISM(S): Lactococcus lactis

SUBMITTER: Vincenzo Fallico 

PROVIDER: E-GEOD-26042 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress