Mussel (Mytilus galloprovincialis) digestive gland tissue: effects of 17β-estradiol injection in reference and Chlorpyrifos pre-exposed animals

ABSTRACT: Transcriptional profiling of mussel (Mytilus galloprovincialis) digestive gland tissue comparing control tissue with tissue obtained from animals exposed to sublethal amounts of Chlorpyrifos, animals injected into the posterior adductor muscle with 25 pico-moles 17β-estradiol (E2) and animals pre-exposed for three days to the pesticide and further injected with E2. Background: Many pesticides have been shown to act as endocrine disrupters. Although the potencies of currently used pesticides as hormone agonists/antagonists in vitro are low compared with those of natural ligands, their ability to act via multiple mechanisms might enhance the biological effect. The organophosphate Chlorpyrifos (CHP) has been shown to be weakly estrogenic and cause adverse neurodevelopmental effects in mammal

ORGANISM(S): Mytilus galloprovincialis

SUBMITTER: Francesco Dondero 

PROVIDER: E-GEOD-26222 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress