Noggin vs BMP4 overexpression Epidermis

ABSTRACT: The study was performed to determine if there were alterations in the total RNA pool among the epidermal keratinocytes of K14 promotor-driven noggin overexpression compared with K14 promotor-driven BMP4 overexpression transgenic animals, which will directly relate to cellular chemistry and immune and sensory function. The total study is also aimed at determining alterations of transcrption factors and/or regulation of gene function, including methylation states and micro RNA control in keratinocytes following sensory challenge, particularly neuropathic and chronic pain conditions. Keywords: Comparison of RNA expression between BMP4-oex and Nog-oex transgenic epidermal keratinocytes Eight-ten epidermis strips were laser captured per animal, and six (6) animals were used per transgenic cond

ORGANISM(S): Mus musculus

SUBMITTER: Sridar Chittur 

PROVIDER: E-GEOD-26231 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress